Gene Panel Testing For Hereditary Breast Cancer

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Genetic testing for hereditary breast and ovarian cancer looks for mutations in the brca1 and brca2 genes.

Gene panel testing for hereditary breast cancer.

These genes can be added at no additional charge. However some clinicians may wish to include genes that may prove to be clinically significant in the future. Gene panel testing for hereditary breast cancer inherited predisposition to breast cancer is explained only in part by mutations in the brca1 and brca2 genes. This single reliable test provides more information for women suspected to have hereditary cancer predisposition particularly for breast and ovarian cancers.

Genetic testing does not detect breast cancer itself it identifies people who are at higher than average risk and helps us to determine the best ways to screen them hilliard said. Genetic testing of these. The breast cancer comprehensive panel examines 20 genes associated with an increased risk for hereditary breast cancer. A multi gene panel test provides better diagnostic yield compared with a limited brca1 2 genetic test for patients at risk for hereditary breast cancer.

The primary panel includes 14 genes associated with hereditary breast cancer. This test includes both well established breast cancer susceptibility genes as well as candidate genes with limited evidence of an association with breast cancer. Is ideal for patients with a clinical suspicion of hereditary breast or ovarian cancer who only wish assessment of genes with established management guidelines. Myriad myrisk captures more mutation carriers than bracanalysis and colaris combined.

Studies have shown that testing with myriad myrisk increases mutation detection between 40 and 50 percent. At this time the association of these genes with breast cancer remains uncertain. In addition to the primary panel clinicians can also choose to include 14 genes that have preliminary evidence of an association with breast cancer.

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